The discovery of slimming capsules which made investing hours in a gym as well as following a strict dieting program redundant to a certain extent, created a rage in the marketplace. They proved to become a blessing in disguise for the whole pharmaceutical industry, which in turn is present day earning of substantial revenues with the sale of these pills. It’s been estimated that greater than twenty million of Americans consume diet pills each year.
The History of Diet Pills
It was during the decade of 1950s when science and medicine were creating striking accomplishments that these capsules had been initially recommended by the doctors to the individuals. The doctors prescribed amphetamines, a drug applied to the World War II to keep soldiers alert and productive, for brown fat and coffee reduction objective. One of the unwanted side effects of amphetamines was appetite suppression that led doctors in prescribing them as diet pills. Eventually many weight loss individuals underwent amphetamines led substance abuse issues along with its prescription was inhibited.
It had been in 1970s when wellness consciousness sprung up to the pinnacle of its as well as fitness became a global craze. Weight reduction became the identity of the game and the pharmaceutical industry saw a sudden boom in the need for them. The first such pills in this era were essentially amphetamines derivatives, normally called “speed”. Afterwards, a wide variety of weight loss pills flooded the market.
Food as well as Drug Administration (FDA) approved the drug fenfluramine (Pondimin) in as early as 1973, that had been followed by dexfenfluramine (Redux) in 1996. After that came the diet drug Phentermine, a sympathomimetic appetite suppressant, that had been approved by the FDA in 1997. Many medical professionals prescribed Phentermine along with fenfluramine. The combined prescription of both prescription drugs was aptly named fen-phen.
The era of fen phen quickly declined with accounts of heart valve disease resulting from the combined utilization of each prescriptions began to surface. The manufacturers withdrew dexfenfluramine as well as fenfluramine from the industry, thereby ending the principle of fen-phen.
The most popular weight minimization medicines which are recommended in the US are sympathomimetic appetite suppressants such as Phentermine. These drugs affect the neurotransmitters in such a way that results in a loss in appetite.
Other diet pills which received FDA approval are Orlistat (Xenical) and Sibutramine (Meridia), which received approval in 1999 as well as 2001 respectively. While Orlistat is a lipase inhibitor that inhibits the absorption of soluble oils to the human body, Sinutramine functions on mind via serotonin, norepinephrine and dopamine reuptake inhibition.