Friday, March 31

The History of Best Diet Pills

The discovery of diet pills which made spending hours in a fitness center as well as following a demanding dieting program redundant to a certain extent, produced a rage in the marketplace. They ended up to be a blessing in disguise for the full pharmaceutical industry, that is today’s earning of substantial revenues with the sale of these pills. It has been estimated that over twenty million of Americans consume diet pills on an annual basis.

The History of Diet Pills

It was during the decade of 1950s when science as well as medicine ended up being producing striking accomplishments that these pills had been initially given by the physicians to the patients. The medical doctors recommended amphetamines, a drug moved to the World War II to keep soldiers alert and productive, for weight loss purpose. Among the negative effects of amphetamines was appetite suppression that led doctors in prescribing them as weight loss supplements. Soon many weight loss patients underwent amphetamines led substance abuse problems along with its prescription was inhibited.

It had been in 1970s when wellness consciousness sprung up to its pinnacle as well as fitness became a world wide craze. Weight reduction became the identity of the game and the pharmaceutical industry saw an unexpected boom in the demand for them. The early such drugs in this era were basically amphetamines derivatives, normally referred to as “speed”. Afterwards, an assortment of fat loss pills flooded the market.

Food and Drug Administration (FDA) approved the drug fenfluramine (Pondimin) in as early as 1973, that was followed by dexfenfluramine (Redux) in 1996. After that came the diet drug Phentermine, a sympathomimetic appetite suppressant, that had been authorized by the FDA in 1997. Numerous medical professionals prescribed Phentermine along with fenfluramine. The combined prescription of each drugs was aptly named fen-phen.

The era of fen-phen quickly declined with reports of heart valve disease resulting from the combined utilization of both prescriptions started to surface. The manufacturers withdrew dexfenfluramine and fenfluramine from the market, thereby ending the principle of fen-phen.

The most common weight minimization drugs that are recommended in the US are sympathomimetic appetite suppressants such as Phentermine. These medications impact the neurotransmitters in such a way that causes a loss in appetite.

Other weightloss pills that received FDA approval are Orlistat (Xenical) and Sibutramine (Meridia), which received approval in 1999 and 2001 respectively. While Orlistat is a lipase inhibitor which prevents the absorption of dietary oils into the body, Sinutramine functions on brain through serotonin, alpilean reviews good reviews norepinephrine as well as dopamine reuptake inhibition.

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