The discovery of diet pills which made investing hours in a workout room as well as adhering to a strict dieting program redundant to a specific extent, created a rage in the marketplace. They turned out to become a blessing in disguise for the entire pharmaceutical industry, which in turn is present day earning of massive revenues with the purchase of these drugs. It has been estimated that over twenty million of Americans consume diet plan pills on an annual basis.
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It was during the decade of 1950s when science and medicine ended up being making striking achievements that these products were initially prescribed by the physicians for the patients. The physicians prescribed amphetamines, a drug used in the World War II to maintain soldiers alert and active, for weight loss objective. Among the unwanted side effects of amphetamines was appetite suppression that led doctors in prescribing them as diet pills. Before long many weight loss patients underwent amphetamines led substance abuse issues and its prescription was inhibited.
It had been in 1970s when wellness consciousness sprung up to the pinnacle of its and fitness became a global craze. Weight reduction became the title of the game as well as the pharmaceutical industry saw an unexpected boom in the demand for them. The early such drugs in this era were basically amphetamines derivatives, normally referred to as “speed”. Later, an assortment of fat reduction capsules flooded the market.
Food as well as Drug Administration (FDA) approved the drug fenfluramine (Pondimin) in as early as 1973, that had been followed by dexfenfluramine (Redux) in 1996. Next came the diet drug Phentermine, a sympathomimetic appetite suppressant, which was approved by the FDA in 1997. Many health professionals prescribed Phentermine in conjunction with fenfluramine. The combined prescription of both the prescriptions was aptly named fen phen.
The era of fen-phen soon declined with reports of heart valve disease resulting from the combined utilization of both drugs started to surface. The makers withdrew fenfluramine and dexfenfluramine from the market, thereby ending the rule of fen-phen.
The most used weight minimization medications that are given in the US are sympathomimetic appetite suppressants like Phentermine. These drugs impact the neurotransmitters in a way that triggers a loss in appetite.
Many other weight loss supplements that received FDA approval are Orlistat (Xenical) and Sibutramine (Meridia), which received approval in 1999 as well as 2001 respectively. While Orlistat is a lipase inhibitor that prevents the absorption of dietary fats into the human body, Sinutramine functions on mind via serotonin, norepinephrine and dopamine reuptake inhibition.