Tuesday, March 21

The History of Best Diet Pills

The discovery of diet pills which made investing hours in a fitness center and also adhering to a rigorous dieting program redundant to a certain extent, produced a rage in the market. They proved to be a blessing in disguise for the full pharmaceutical industry, that is today’s earning of substantial revenues with the sale of these drugs. It’s been estimated that more than twenty million of Americans consume diet drugs each year.

The History of Diet Pills

It was during the decade of 1950s when science and medicine were producing striking achievements that these products had been initially recommended by the physicians to the individuals. The physicians recommended amphetamines, a drug used in the World War II to keep soldiers alert and alpilean reviews buy productive, for fat reduction purpose. One of the negative effects of amphetamines was appetite suppression which led doctors in prescribing them as weight loss supplements. Before long many weight loss patients underwent amphetamines led substance abuse issues as well as its prescription was inhibited.

It was in 1970s when wellness consciousness sprung up to the pinnacle of its as well as fitness became a world wide craze. Weight reduction became the name of the game as well as the pharmaceutical industry saw an unexpected boom in the demand for them. The first such drugs in this era were essentially amphetamines derivatives, normally known as “speed”. Afterwards, an assortment of fat reduction capsules flooded the market.

Food and Drug Administration (FDA) approved the drug fenfluramine (Pondimin) in as early as 1973, that had been followed by dexfenfluramine (Redux) in 1996. Then came the diet drug Phentermine, a sympathomimetic appetite suppressant, which was authorized by the FDA in 1997. Numerous medical professionals prescribed Phentermine in conjunction with fenfluramine. The combined prescription of both the prescriptions was aptly named fen phen.

The era of fen-phen soon declined with reports of heart valve disease resulting from the combined usage of both the prescriptions started to surface. The manufacturers withdrew dexfenfluramine as well as fenfluramine from the industry, therefore ending the principle of fen-phen.

The most used weight minimization medicines that are given in the US are sympathomimetic appetite suppressants like Phentermine. These drugs impact the neurotransmitters in such a way that results in a loss in appetite.

Other weightloss pills which received FDA approval are Orlistat (Xenical) and Sibutramine (Meridia), which received approval in 1999 and 2001 respectively. While Orlistat is a lipase inhibitor which prevents the absorption of dietary fats to the human body, Sinutramine functions on mind through serotonin, norepinephrine and dopamine reuptake inhibition.

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